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. 2024 Jun 14;15:1416555. doi: 10.3389/fphar.2024.1416555

TABLE 13.

Results of the selected studies examining T cell immunotherapy in treating ovarian cancer.

Name of the study Year of the study Phase of the study Research group Dose Results
Kershaw et al. (Kershaw et al., 2006) 2006 I 14 3 × 109–5 × 1,010 transduced T cells There were observed some grade 3 and 4 toxicities in the group with high-dose usage of IL-2; in the group, which received T cells without IL-2, patients experienced relatively mild side effects; there was not observed any tumor burden in patients
Dobrzanski et al. (Dobrzanski et al., 2012) 2012 Phase I/II 7 108–109 T cells per infusion (i.e. 1–4 × 108 cells/m2) There was observed enhanced patient survival in 3 monthly treatment cycles (3->84 months)

IL, interleukin.