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. 2024 Jun 14;30(22):2881–2892. doi: 10.3748/wjg.v30.i22.2881

Table 2.

Association between heparin use and clinical outcomes


Heparin-free group, n (%)
Heparin group, n (%)
OR (95%CI)
P value
Before PSM n = 421 n = 967
PHLF 66 (15.7) 76 (7.9) 2.180 (1.533, 3.099) < 0.001
ICU stay 79 (18.8) 129 (13.3) 1.501 (1.104, 2.040) 0.010
Respiratory support 70 (16.6) 72 (7.4) 2.479 (1.745, 3.523) 0.000
CRRT 17 (4) 8 (0.8) 5.044 (2.160, 11.782) < 0.001
Hypoxemia 39 (9.3) 48 (5.0) 1.955 (1.260, 3.032) 0.003
AKI 40 (9.5) 66 (6.8) 1.433 (0.951, 2.161) 0.086
ICU death 43 (10.2) 43 (4.4) 2.354 (1.543, 3.593) < 0.001
After PSM n = 213 n = 213
PHFL 45 (21.1) 28 (13.1) 0.530 (0.303, 0.928) 0.026
ICU stay 49 (23.0) 51 (23.9) 1.722 (0.933, 3.177) 0.082
Respiratory support 43 (20.2) 30 (14.1) 0.502 (0.262, 0.960) 0.037
CRRT 5 (2.3) 4 (1.9) 1.059 (0.249, 4.496) 0.939
Hypoxemia 23 (10.8) 23 (10.8) 1.181 (0.598, 2.334) 0.631
AKI 22 (10.3) 21 (9.9) 1.017 (0.525, 1.971) 0.960
ICU death 27 (12.7) 24 (11.3) 0.956 (0.469, 1.949) 0.901

Bivariate logistic regression analysis with patients before and post propensity score matching was all applied to investigate variables potentially associated with all secondary clinical outcomes. PSM: Propensity score matching; CRRT: Continuous renal replacement therapy; PHFL: Post-hepatectomy liver failure; AKI: Acute kidney injury.