Table 3.
Peripheral vascular responses during incremental lower-body negative pressure
| BL |
LBNP |
P Values |
||||||
|---|---|---|---|---|---|---|---|---|
| 0 mmHg | −10 mmHg | −20 mmHg | −30 mmHg | −40 mmHg | Group | Condition | Interaction | |
| Brachial Artery Diameter, cm | ||||||||
| Control | 0.47 ± 0.09 | 0.46 ± 0.09 | 0.45 ± 0.08# | 0.45 ± 0.09# | 0.44 ± 0.09# | 0.62 | <0.01 | 0.14 |
| HFpEF | 0.44 ± 0.08 | 0.44 ± 0.08 | 0.43 ± 0.08# | 0.43 ± 0.08# | 0.43 ± 0.08# | |||
| Mean blood velocity, cm/s | ||||||||
| Control | 9.1 ± 3.0 | 7.9 ± 3.0 | 7.5 ± 2.8 | 7.4 ± 2.5 | 7.3 ± 2.4 | 0.30 | <0.01 | 0.58 |
| HFpEF | 10.3 ± 4.0 | 9.8 ± 3.9 | 9.2 ± 3.5 | 9.1 ± 3.5 | 8.8 ± 3.5 | |||
| Forearm blood flow, mL/min | ||||||||
| Control | 90 ± 28 | 76 ± 27# | 70 ± 23# | 68 ± 22# | 65 ± 21# | 0.52 | <0.01 | 0.50 |
| HFpEF | 93 ± 34 | 87 ± 36 | 78 ± 26# | 77 ± 27# | 74 ± 26# | |||
| Forearm vascular conductance, mL/min/mmHg | ||||||||
| Control | 0.95 ± 0.29 | 0.81 ± 0.26# | 0.74 ± 0.21# | 0.72 ± 0.21# | 0.68 ± 0.19# | 0.21 | <0.01 | 0.57 |
| HFpEF | 1.09 ± 0.44 | 1.03 ± 0.44 | 0.92 ± 0.34# | 0.91 ± 0.35# | 0.88 ± 0.34# | |||
Values are means ± SD. BP, blood pressure; HR, heart rate; MAP, mean arterial pressure. Two-way repeated measures ANOVA (group × time). #P < 0.05 vs. BL (0 mmHg).