Table I:

Group characteristics

	CTRL	DS	DS-CA
N = 81	18	30	33
Axis 1 diagnosis	0	MDD (25); DD-NOS (5)	MDD (26); DD-NOS (7)
Age (years) (P = 0.06)	48.1 ± 20.2	50.4 ± 12.5	41.5 ± 14.6
Sex (M/F)	13/5	25/5	22/11
PMI (h) (P = 0.14)	41.1 ± 25.0	54.0 ± 29.0	56.9 ± 27.7
Tissue pH (P = 0.99)	6.5 ± 0.3	6.5 ± 0.4	6.5 ± 0.4
Substance dependence	0	8	8
Last 3 months medication	Sedative hypnotics (1)	Classic antidepressants (4); Benzodiazepines (9); SNRI (4); SSRI (6); Antipsychotic (3); TCA (2); Antimanic (1); Opioid (1)	Classic antidepressants (2); Benzodiazepines (6); SNRI (3); SSRI (7); Antipsychotic (3); TCA (1); Antimanic (1); Opioid (2); NASSA (2); SARI (1); Anticonvulsant (2); GABA analog (1)