Figure 6.

A) Chromosome diagrams depict the translocation between 8q21.13 and 14q12 in NIJ1. Above, TADs containing the breakpoints are shown, with the breakpoint positions indicated by vertical yellow bars. Protein-coding genes are shown in blue and non-coding genes in green, with a single isoform depicted per gene. TAD borders were defined in (Dixon et al. 2012). Triangular contact maps display micro-C data from (Krietenstein et al. 2020). B) Expanded view of the genomic region surrounding the 8q21.13 breakpoints in NIJ1. C) Expanded view of the genomic region surrounding the 14q12 breakpoints in NIJ1. The directly disrupted lncRNAs ENSG00000258028 and ENSG00000257522 are highlighted in red.