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Mapping of lesions within the 8MA-V genome. (A) An in-frame deletion within the vhs gene of 8MA-V removes residues 91 to 354. The location of the in-frame SmaI deletion of ΔSma is shown for comparison. Both the nucleotide and the resulting amino acid sequences are indicated. (B) Two independent point mutations within the UL53 gene of 8MA-V were found that altered residues 103 and 309 (■). Each altered residue is located within an ectodomain where known syncytial mutations reside (●).
