Figure 7. AMPAergic scaling was absent following 24 hr of 20 µM CNQX.

AMPA mEPSC amplitudes were no different than control following AMPA receptor (AMPAR) blockade (p=0.57, control - n=9 from 4 cultures, CNQX - n=8 from 3 cultures). Recordings from single neurons (filled circles), where mean values (represented by horizontal bar) are plotted, as a bootstrap sampling distribution (mean difference is represented by a filled circles and the 95% CIs are depicted by vertical error bars). All miniature excitatory postsynaptic current (mEPSC) amplitudes recorded from cultures plated on multi-electrode arrays (MEAs).