Table 2. Overview of N-protein species compared in biophysical experiments.

Designation	N-protein mutations	n exclusive instances*	Occur in # of distinct sequences†	Occurs in % of all genomes ‡	In set of defining VOC mutations §
N:R203K/G204R	R203K, G204R	53,282	17,552	57%	α, γ, ο
N:P13L/Δ31–33	P13L, Δ31–33	9548	12,503	47%	ο
Nο	P13L, Δ31–33, R203K, G204R	791,613	10,238	46%	ο (all BA.1)¶
Nδ	D63G, R203M, G215C, D377Y	>1.2 × 106	9397	33%	δ (all 21J)¶
N:G215C	G215C	60	10,562	34%	δ
N:D63G	D63G	182	12,443	36%	δ
Nref	none	38,929	NA	3.6%	NA

^*Number of genomes where the indicated mutations are the only N mutations.

^†Number of unique N-protein sequences in which indicated mutations are present, alongside other mutations.

^‡Percentage of all sequenced genomes carrying the specific mutation.

^§Variants of concern for which indicated mutations are part (or all) of the defining set of N-m.

^¶These sets of mutations comprise all defining N-protein mutations of this variant. Literature on definition or biophysical characterization of the mutant.