TABLE 3.
Replication of A/teal/Hong Kong/W312/97 (H6N1) influenza virus in mice
| Virusa | Virus titer
|
MLD50 (EID50)b | % wt loss on day 3 after infection | Titer of virus on day 3 after infection (log EID50/ml)
|
||
|---|---|---|---|---|---|---|
| In eggs (log EID50) | In mice (log MLD50) | Lungs | Brain | |||
| A/Hong Kong/156/97 | 9.0 | 7.7 | 1.16 | 15 | 8.5 | 2.0 |
| A/Teal/Hong Kong/W312/97 | ||||||
| P0 | 8.5 | 1.0 | 8.5 | 24 | 8.5 | None |
| P1 | 7.2 | Not studied | Not studied | Not studied | 7.5 | None |
| P2 | 8.0 | Not studied | Not studied | Not studied | 8.5 | 1.0 |
| P3 | 8.2 | 3.5 | 2.3 | 25 | 8.0 | 2.5 |
a
P0, original isolate; P1 to P3, infection with A/teal/Hong Kong W312/97 after passage 1, 2, or 3 times, respectively, in mouse lungs, with subsequent propagation in embryonated chicken eggs.
b
MLD50 (EID50), quantity of infectious virus units (EID50) in 1 MLD50.