Table 1.

Quantitative comparison of virtual H&E staining on two TMA sections of lung cancerous tissues from intensity, α-FLIM, and IW-FLIM using the normalised root-mean-squared error (NRMSE), the normalised mutual information (MNI), the peak signal-to-noise ratio (PSNR), and the mean structural similarity index metric (MSSIM).

		NRMSE	NMI	PSNR	MSSIM
Lung sample 1 (Fig. 1a)	Intensity	0.127	1.093	20.085	0.529
	a-FLIM	0.127	1.091	20.121	0.53
	IW-FLIM	0.126	1.096	20.202	0.533
Lung sample 2 (Fig. 1c)	Intensity	0.095	1.154	22.767	0.689
	a-FLIM	0.093	1.161	22.962	0.695
	IW-FLIM	0.092	1.164	23.026	0.697

Note that smaller NRMSE and NMI indicate more similar images, whereas larger PSNR and MSSIM represent better similarity between images.