Kumar 2013.

Methods	Prospective, randomised placebo‐controlled single centre study
Participants	60 patients (30 silodosin, 30 placebo). Mean age (SD): Group A: 64.5 (9.3) Group B: 65.8 (8.1)
Interventions	A (30): Silodosin 8 mg once daily for 3 days B (30): placebo
Outcomes	Number who had successful TWOC: A 23/30, B 11/30 Factors influencing TWOC failure Effects of silodosin on uroflowmetry and IPSS in patients who had successful TWOC
Notes	Study conducted in tertiary care regional referral centre in Northern India Successful TWOC: ‘If the patient voided successfully, a postvoid bladder scan was performed to measure his residual urine volume.  If there was less than 150 mL postvoid residual volume after voiding at least 100 mL of urine, he was considered to have a successful TWOC.’ Failed TWOC: ‘...if the patient re‐experienced painful AUR or if the PVR urine volume was >150 mL, he was re‐catheterised and considered to have a failed TWOC.’
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	‘...centrally established computer‐assigned randomization list...’
Allocation concealment (selection bias)	Unclear risk	Not specified
Incomplete outcome data (attrition bias) All outcomes	Low risk	No incomplete outcome data
Selective reporting (reporting bias)	Unclear risk	All the outcomes as detailed in the method section of the trial were reported in the result section. Some outcomes which are considered important from patients’ perspective were not reported. Without the protocol it was difficult to judge whether or not these outcomes were included in the protocol and not reported in the report.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Placebo administered was ‘similar to silodosin capsule in colour, weight, and shape’ Unclear if personnel were blinded.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not specified
Other bias	Low risk	Study groups were comparable at baseline Power calculation was performed Ethical approval obtained Written informed consent obtained No withdrawals/loss to follow‐up