Table 1.
Cohort Description for DN-NMOSD, AQP4-NMOSD, and HCs
| DN-NMOSD | AQP4-NMOSD | HC | |
| Subjects, N | 25 | 25 | 25 |
| Eyes, N | 48 | 46 | 49 |
| Ethnicity, N (%) | |||
| Asian | 2 (8) | 9 (36) | 4 (16) |
| White | 23 (92) | 15 (60) | 21 (84) |
| Other | 0 (0) | 1 (4) | 0 (0) |
| Age, year, mean ± SD | 32 ± 8 | 33 ± 8 | 31 ± 7 |
| Sex, male, N (%) | 7 (28) | 3 (12) | 9 (36) |
| EDSS, median (IQR) | 2 (1–3) | 1.5 (1–3.75) | |
| Time since onset, year, mean ± SD | 5 ± 4 | 7 ± 6 | |
| Eyes with a history of ON, N (%) | 23 (48) | 28 (61) |
Abbreviation: AQP4-NMOSD = people with aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder; DN-NMOSD = people with double-antibody seronegative neuromyelitis optica spectrum disorder; HC = healthy control; IQR = interquartile range; N = number.