FIG. 2.

Serum CDV-neutralizing antibody titers in ferrets vaccinated parenterally at ages 3 (s.c.) and 6 (i.m.) weeks in the presence of maternal antibody. Vaccines included NYVAC (NY-HF; n = 7) and ALVAC (AL-HF; n = 7) vectors expressing CDV H and F proteins, an attenuated, live-virus CDV vaccine (atten. CDV; n = 7), and the NYVAC and ALVAC vectors expressing RG (AL-RG [n = 4] and NY-RG [n = 4]) (NY/AL-RG). Ferrets were challenged i.n. with virulent CDV at 12 weeks of age. Values shown are mean ± SD inverse log₁₀ titers from samples collected just prior to vaccination or challenge, as indicated. Asterisks indicate means that are significantly lower than the other means at the same time.