Fig. 1.

Schedule of LSECs morphology and function research. The graph shows the main findings of LSECs in the progress of MAFLD. The line chart reflects the total number of publications targeting LSECs in recent years. The research content pointed by the arrows provide a basis for us to understand the morphological structure (lower box) and physiological or pathological function of LSECs (upper box). In the past few decades, publications in this field have rapidly increased, and some targets related to LSECs have entered clinical research through basic trials, all of which are discussed in more detail in this text