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. 2024 May 22;27(6):110045. doi: 10.1016/j.isci.2024.110045

Figure 10.

Figure 10

After the inhibition of PPP pathway, oxidative stress induced by inflammatory factors, cell aging and fibrosis were alleviated (n = 3)

(A) Images of SA-β-galactosidase-positive cells. Scale bars: 100mm.

(B) Positive cell rate statistical results.

(C) Protein bands of P16, P21, P53, γH2AX，COL-I，COL-III of cells of each group.

(D–I) Quantitative analysis results of P16, P21, P53, γH2AX，COL-I，COL-III.

(J) Results of ROS content in cells of each group.

(K) Results of DHE content in cells of each group.

(L) Results of T-SOD content in cells of each group. Data shown as mean ± SD. ∗＜0.05，∗∗＜0.01，∗∗∗＜0.001, ∗∗∗∗＜0.0001 versus the Normal-control group, #＜0.05, ##＜0.01，###＜0.001，####＜0.0001 versus the Normal-siNC group，▲＜0.05，▲▲＜0.01，▲▲▲＜0.0001，versus the TNF-α-control group，◆＜0.05, ◆◆＜0.01，◆◆◆＜0.001 versus the IL-6-control group.