Fig. 5.

Electroacupuncture treatment for six consecutive weeks alters the aortic lipid pattern in SHR. (A) Scheme of iterative MS/MS. (B) Number of identified lipid features acquired from the iterative MS/MS analysis. Representative total ion chromatograms (left), PLS-DA score plots (middle), and 100-fold permutation plots (right) derived from positive (C) or negative (D) modes of the UHPLC Q-TOF system. EA, electroacupuncture; WKY, Wistar-Kyoto rat; SHR, spontaneously hypertensive rat; SHR+EA, EA-treated SHR; MS/MS, tandem mass spectrometry; ESI TIC, electrospray ionization total-ion current; PLS-DA, partial-least-squares discriminant analysis; UHPLC Q-TOF, ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry.