REAGENT or RESOURCE	SOURCE	IDENTIFIER
Deposited data
deCODE (protein)	Ferkingstad et al.14	https://www.decode.com/summarydata/
UKB-PPP (protein)	Sun et al.15	https://metabolomips.org/ukbbpgwas/
ARIC (protein)	Zhang et al.16	http://nilanjanchatterjeelab.org/pwas/
AGES (protein)	Emilsson et al.17	https://pubmed.ncbi.nlm.nih.gov/30072576/
INTERVAL (protein)	Sun et al.18	http://www.phpc.cam.ac.uk/ceu/proteins/
UK Biobank (TC)	Feng et al.19	https://www.ukbiobank.ac.uk/
FinnGen R9 (TC)	-	https://finngen.gitbook.io/documentation/v/r9
Aleksandra et al. (TC)	Aleksandra et al.20	https://www.ebi.ac.uk/gwas/
TCGA	Sanchez-Vega et al.21	https://www.cancer.gov/ccg/research/genome-sequencing/tcga
GTEx	Li et al.22	https://gtexportal.org/home/
GEO	GSE33630; GSE60542	https://www.ncbi.nlm.nih.gov/geo/
Our Multi-omic Cohort	This study	supplemental information
Software and algorithms
R (v 4.3.0)	-	https://www.r-project.org
TwosampleMR (v 0.5.7)	Hemani et al.67	https://www.mrbase.org
Coloc	Giambartolomei et al.68	https://github.com/chr1swallace/coloc
ClusterProfiler	Yu et al.69	https://bioconductor.org/packages/release/bioc/html/clusterProfiler.html
STRING	-	https://cn.string-db.org/
PLINK (v 1.9)	Purcell, S. et al.70	https://www.cog-genomics.org/plink/1.9
GeneMANIA	Warde-Farley71	https://genemania.org/
SMR (v 1.3.1)	Yang et al.72	https://yanglab.westlake.edu.cn/software/smr/#Overview
METAL	Willer et al.73	https://genome.sph.umich.edu/wiki/METAL_Documentation