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. 2024 May 14;300(6):107368. doi: 10.1016/j.jbc.2024.107368

Figure 4.

Figure 4

ASCC1 Sequence, secondary structure, and residue function for multi-sequence alignment. ApASCC1Δ40 crystal structure is mapped onto full-length sequence alignment. Fig. S1 maps secondary structure onto crystal structure and positions of tumor VUS with EA score >80 and E292 disease mutant.