Figure 3.

GSK reverses the effects of HS on Th17 and Treg program in vivo

(A) Schematic representation of the adoptive transfer model.

(B and C) The proportion of Th17 cells within splenic CD4 T cells of recipient mice (n = 5).

(D and E) The proportion of Treg cells within splenic CD4 T cells of recipient mice (n = 5).

(F and G) The proportion of activated CD4 T cells within splenic CD4 T cells of recipient mice (n = 5).

(H and I) The proportion of IL-17A producing donor cells in spleen (n = 3). Statistical significance was calculated by unpaired Student’s t test and data are represented as mean ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.