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. 2014 Jul 1;2014(7):CD007331. doi: 10.1002/14651858.CD007331.pub3

Assefa 2012.

Methods Design: retrospective cohort
 Duration of study: recruitment September 2006 ‐ 2008, censored March 2009 (minimum 6 months, maximum 24 months follow‐up)
Participants Country: Ethiopia
 Setting: nationwide, 30 hospitals, 25 health centres
 Inclusion and exclusion criteria: nil described
 Comparable CD4 count or clinical stage at baseline: similar CD4 count
Interventions Intervention: patients initiated and maintained at health centres by nurses and health officers. Severe manifestations, treatment failures were referred to hospital.
 Control: initiated and followed up at hospital with physicians.
 Co‐interventions: community health workers performed counselling, referrals and linkage between facilities and defaulter tracing in both groups
Outcomes Mortality, loss to follow‐up, retention, and median CD4 Count.
 Assessed at 6, 12 and 24 months
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Baseline CD4 count (All studies) Low risk Similar median CD4 count in both groups
Other baseline variables (All studies) Unclear risk Not described
Co‐ interventions (All studies) Unclear risk Community health workers delivered adherence and referral services from health centres to hospitals, unclear whether this was for both groups or for the health centre group only
Data collection (Cohorts) High risk Retrospective cohort
Patient selection bias (Cohorts) Low risk  Randomly selected folders in all included sites in both groups