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. 2024;24(1):73–79. doi: 10.24911/SJP.106-1679595787

Table 1.

Difference in MIS-C diagnostics criteria between the Royal College of Paediatrics and Child Health (RCPCH), CDC, and the World Health Organization (WHO).

Differences RCPCH CDC WHO
Name PIMS-temporally associated with COVID-19 MIS-C MIS-C
Length of fever Not specified ≥24 hours ≥3 days
Age Child <21 years 0 to 19 years
Evidence of inflammation Yes Yes Yes
Multisystem involvement Single organ or multisystem ≥2 systems involved ≥2 systems involved
Exclude other causes Yes Yes Yes
SARS-CoV-2-PCR or antibody or exposure Not necessary Necessary Necessary

MIS-C, multisystem inflammatory syndrome in children; PIMS, Paediatric inflammatory multisystem syndrome; SARS-CoV-2, COVID19; PCR, Polymerase Chain Reaction.