Table 3.

Outcomes by Vasopressor Initiation Route

Variable	Peripheral Initiation (n = 400)	Central Initiation (n = 154)	Adjusted ORa (95% CI)
In-hospital mortalityb	129 (32.3)	65 (42.2)	0.66 (0.39-1.12)
30-d mortality	162 (40.5)	75 (48.7)	0.76 (0.45-1.27)
90-d mortality	187 (46.8)	84 (54.5)	0.77 (0.46-1.28)
Mechanical ventilation during admission	178 (44.5)	76 (49.4)	0.96 (0.47-1.98)
New dialysis during admission	29 (7.3)	14 (9.1)	0.78 (0.34-1.77)
Hospital length of stay > 7 d	163 (40.8)	68 (44.2)	0.88 (0.56-1.38)
Central line removed because of complication	2 (0.5)	2 (1.3)	Not applicablec

Data are presented as No. (%), unless otherwise indicated. N = 554 patients with vasopressors initiated through peripheral IV or central line. Patients with other routes of initiation were excluded. BMI was missing for 33 patients and was imputed using age and sex.

^aMultilevel logistic regression models, adjusted for age, place of resident before admission, hospitalization in prior 90 d, chronic kidney disease, chronic liver disease, congestive heart failure, peripheral vascular disease, malignancy, BMI, maximum initial lactate, maximum creatinine day 1, mechanical ventilation within 6 h of arrival, altered mental status, and predicted mortality score.

^bPrimary outcome.

^cRegression model not performed because of low event rate.