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TABLE 1.

Soluble GAG competition in paramyxoviruses

Virus Mean GAG ED50 (μg/ml)a ± SEM
LMW heparin BVL heparin De-N-sulfated heparin Chondroitin sulfate
A2 28.11 ± 0.23 0.28 ± 0.11 29.96 ± 0.42 85 ± 6.8
cp-52 3.38 ± 0.17 0.55 ± 0.14 3.46 ± 0.54 11.5 ± 1.94
Measles virusb >250 >250 >250 >250
a

Results represent the mean ± the standard error of the mean for at least four separate experiments (P < 0.05). 

b

Inhibition of measles virus infectivity did not exceed 50% for any of the GAGs tested, and therefore no ED50 could be calculated.