TABLE 1.
Soluble GAG competition in paramyxoviruses
Virus | Mean GAG ED50 (μg/ml)a ± SEM
|
|||
---|---|---|---|---|
LMW heparin | BVL heparin | De-N-sulfated heparin | Chondroitin sulfate | |
A2 | 28.11 ± 0.23 | 0.28 ± 0.11 | 29.96 ± 0.42 | 85 ± 6.8 |
cp-52 | 3.38 ± 0.17 | 0.55 ± 0.14 | 3.46 ± 0.54 | 11.5 ± 1.94 |
Measles virusb | >250 | >250 | >250 | >250 |
Results represent the mean ± the standard error of the mean for at least four separate experiments (P < 0.05).
Inhibition of measles virus infectivity did not exceed 50% for any of the GAGs tested, and therefore no ED50 could be calculated.