Figure 2.

Clinical response and undetectable minimal residual disease rate at different time points. (A) Individual minimal residual disease (MRD) status, clinical response, and outcome at different times. (B) Undetectable MRD rate at different time points. ER: early restaging at 4 months; EOT: end of treatment at 6 months; FU-1: 1-year follow-up; FU2: 2-year follow-up; Last-FU: last available control. Red dot: MRD⁺ (at least 1 MRD-positive sample, either bone marrow [BM] or peripheral blood [PB]); blue spot: MRD^- (unmeasurable MRD); black dot: dead; CR: complete remission; PR: partial remission; SD: stable disease; R: relapse; P: progression; green arrow: alive at last FU.