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. 2024 Jul 1;14(29):20536–20542. doi: 10.1039/d4ra02968b

Inhibitory activity of compounds 1–8 on the NO production in LPS-activated RAW264.7 cells.

Comp IC50 (μM) Comp IC50 (μM)
1 25.3 ± 1.5 5 20.2 ± 2.4
2 37.7 ± 2.1 6 31.1 ± 2.7
3 16.8 ± 1.0 7 36.6 ± 1.8
4 18.8 ± 1.4 8 10.2 ± 0.2
l-NMMAa 31.5 ± 2.6
a

NG-monomethyl-l-arginine acetate salt (l-NMMA) was as a positive control.