Table 3.
Summary of response rate in the full analysis set by dose level.
| CAR T-cell dose | DL1 (3 × 107) | DL2 (1 × 108) | DL3 (3 × 108) | DL4 (9 × 108) | Total |
|---|---|---|---|---|---|
| N = 3 | N = 3 | N = 6 | N = 4 | N = 16 | |
| ORR (CR + PR), n (%) | 1 (33.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (6.3) |
| CR, n (%) | 1 (33.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (6.3) |
| DCR (CR + PR + SD), n (%) | 3 (100.0) | 2 (66.7) | 4 (66.7) | 4 (100.0) | 13 (81.3) |
| SD, n (%) | 2 (66.7) | 2 (66.7) | 4 (66.7) | 4 (100.0) | 12 (75.0) |
Abbreviations: CAR, chimeric antigen receptor; CR, complete response; DCR, disease control rate; DL, dose level; ORR, overall response rate; PR, partial response; SD, stable disease.