Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jul 1;223(9):e202311126. doi: 10.1083/jcb.202311126

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 Li et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — COSIMA analysis of ER-LD and mito-LD contact sites. (A) A flowchart describing the COSIMA pipeline. (B) Circumference of lipid droplets (LDs) analyzed by COSIMA in the endoplasmic reticulum (ER)-LD and mitochondria (mito)-LD group. Raw data and mean ± SD are shown (39–60 LDs). n.s. = not significant, assessed by two-tailed t test. (C) Size of ER-LD and mito-LD contact sites measured by COSIMA. Raw data and mean ± SD are shown (81–99 contact sites). n.s. = not significant, assessed by two-tailed t test. (D and E) Population distribution of domain size of ER-LD (D) and mito-LD (E) contact sites. Bar graphs show raw data and traces represent fitted bi-modal Gaussian distributions (N). Each N is shown as (mean, SD); % of raw data. (F) Number of ER-LD and mito-LD contact sites on each LD. Raw data and mean ± SD are shown (39–60 LDs). *P ≤ 0.05, assessed by two-tailed t test. (G) Fraction of LD’s perimeter covered by ER-LD and mito-LD contact sites. Raw data and mean ± SD are shown (39–60 LDs). ***P ≤ 0.001, assessed by two-tailed t test.