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. 2024 Jun 12;67(12):10401–10424. doi: 10.1021/acs.jmedchem.4c00855

Figure 5.

Figure 5

Mouse PK profiles of ARN25499 (15) and ARN25375 (20) following intravenous (I.V.) and oral (P.O.) administration at 3 and 10 mg/kg, respectively, and the corresponding observed and calculated PK parameters.