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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Ann N Y Acad Sci. 2023 Jun 30;1526(1):50–58. doi: 10.1111/nyas.15033

Figure 3. Proposed mechanism of replication of H3K4me2 during transcriptional memory.

Figure 3.

Following DNA replication, SET3C recognizes the H3K4me2 mark near the promoter of genes that exhibit memory. Through interaction with Spp1− COMPASS, potentially involving the Paf1C complex subunit Leo1, SET3 recruits COMPASS to this site and re-establishes H3K4me2.