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Synthesis of compounds 6a–11. Reagents and conditions: (A) Aromatic aldehydes, EtOH, HOAc, reflux 3–6 h. (B) Substituted acetophenone, EtOH, HOAc, reflux, 6–18 h. (C) Aldehydes 5a–c, EtOH, HOAc, reflux, 4–8 h. (D) Isatin derivative EtOH, HOAc, reflux 8 h. (E) Chalcones 4a–c, EtOH, HOAc, reflux, 24 h. (F) 2-tetralone EtOH, HOAc, reflux 6 h.
