Table 4.

Low risk reclassification for Cardiovascular Events and heart failure (HF) by AI-CAC enlarged left atrium (LA) and left ventricle (LV) in participants with Agatston coronary artery calcium (CAC) score of 0 or ASCVD Pooled Cohorts Equation (PCE) 10-year risk estimate below 5%.

	ASCVD PCE Risk Estimate <5% & Top Quartile LA or LV	CAC 0 & Top Quartile LA or LV
15-year follow-up All Cardiovascular Events* (n = 1732)	197 (11.3%)	501 (28.9%)
HF (n = 292)	18 (6.2%)	71 (24.3%)
10-year follow-up All Cardiovascular Events* (n = 674)	72 (10.7%)	259 (38.4%)
HF (n = 212)	13 (6.1%)	50 (23.6%)
5-year follow-up All Cardiovascular Events* (n = 311)	32 (10.3%)	116 (37.3%)
HF (n = 106)	5 (4.7%)	24 (22.6%)

All Cardiovascular Events: stroke, myocardial infarction, angina, resuscitated cardiac arrest, all cardiovascular disease related deaths, HF, and atrial fibrillation.