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. 2024 Mar 22;38(7):1600–1603. doi: 10.1038/s41375-024-02209-7

Fig. 1. Comparison of KMT2A-based and IG/TR-based MRD measurements.

Fig. 1

A Comparison of MRD levels with KMT2A and IG/TR targets in KMT2A-rearranged adult ALL patients. MRD measurements with data on both KMT2A and IG/TR were available from 46 patients totaling 373 sample pairs from peripheral blood or bone marrow aspirates. MRD levels were plotted against each other from negative (neg), positive (pos)< quantifiable range (QR), and quantifiable range in logarithmic format. Black circles represent MRD concordant samples and red circles discordant samples. B Comparison of KMT2A and IG/TR MRD levels over time. All MRD-levels (n = 523) with data on both IG/TR and KMT2A were sorted into four groups (gray color IG/TR and KMT2A MRD level concordant and negative (neg.), blue color IG/TR and KMT2A MRD level discordant with higher IG/TR MRD category, yellow color IG/TR and KMT2A MRD level concordant and positive, and red color IG/TR and KMT2A MRD level discordant with higher KMT2A MRD category) and plotted against days after initial diagnosis (ID).