Drug	No of studies	Pooled relative risk (95% CI)†	P value (heterogenicity)
Ibuprofen	NA	1.0	NA
Fenoprofen	2	1.6 (1.0 to 2.5)	0.310
Aspirin	6	1.6 (1.3 to 2.0)	0.685
Diclofenac	8	1.8 (1.4 to 2.3)	0.778
Sulindac	5	2.1 (1.6 to 2.7)	0.685
Diflunisal	2	2.2 (1.2 to 4.1)	0.351
Naproxen	10	2.2 (1.7 to 2.9)	0.131
Indometacin	11	2.4 (1.9 to 3.1)	0.488
Tolmetin	2	3.0 (1.8 to 4.9)	0.298
Piroxicam	10	3.8 (2.7 to 5.2)	0.087
Ketoprofen	7	4.2 (2.7 to 6.4)	0.258
Azapropazone	2	9.2 (4.0 to 21.0)	0.832