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. 2024 Jun 18;15:1327984. doi: 10.3389/fgene.2024.1327984

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Copyright © 2024 Rezapour, Walker, Ornelles, Niazi, McNutt, Atala and Gurcan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Top 10 Significant Gene Ontology (GO) Processes for Upregulated Genes in IAV-None-72 versus Mock-72 Comparison: This bar graph ranks the top 10 out of 573 significant GO processes based on q-values for BH-significantly upregulated genes identified in the IAV-None-72 versus Mock-72 comparison across both RNA-Seq and NanoString platforms. Each bar represents a GO process, with its length corresponding to the -log10 (q-value), indicating the statistical significance. The descriptions highlight the number of genes involved and key genes associated with each process, such as IFIT1, CXCL10, and RSAD2, demonstrating the host’s robust antiviral and immune response.