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. 2000 Jul;74(14):6632–6636. doi: 10.1128/jvi.74.14.6632-6636.2000

TABLE 1.

TIL recognize autologous tumor cellsa

Target Blocking MAb IFN-γ (pg/ml/106 cells)
Tumor None 0
TIL None 23
Tumor + TIL None 400
W6/32 400
L243 20
a

Autologous cervical cancer cells harboring HPV33 were tested for T-cell recognition as determined by IFN-γ and IL-2 secretion by ELISA. TIL secreted IFN-γ, but not IL-2 in response to tumor cells, which could be blocked with the anti-DR-directed MAb L243. Blocking with the anti-DR-directed MAb clone B8.12.2 showed a similar result in a parallel experiment.