Table 2.

Multivariate linear regression analysis for the independent associations among SII, cIMT and CT_L-S.

Independent variables	Dependent variables	Model 1		Model 2		Model 3
		β	P value	β	P value	β	P value
SII	cIMT	0.323	<0.001	0.189	<0.001	0.168	<0.001
SII	CTL-S	-0.306	<0.001	-0.159	<0.001	-0.147	<0.001
cIMT	CTL-S	-0.374	<0.001	-0.255	<0.001	-0.243	<0.001

Model 1: adjusted for age, gender, diabetic duration, smoking, and drinking.

Model 2: further adjustments for cardiometabolic variables, such as systolic blood pressure, diastolic blood pressure, waist circumference, body mass index, glycated hemoglobin, triglycerides, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and homeostatic model assessment of insulin resistance.

Model 3: additional adjustments for liver functional variables like alanine aminotransferase and aspartate aminotransferase.

SII, Systemic immune-inflammation index; cIMT, Carotid intima-media thickness; CT_L-S, CT liver-spleen attenuation measurement.