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. Author manuscript; available in PMC: 2025 Jan 18.
Published in final edited form as: J Assoc Nurses AIDS Care. 2024 Jan 18;35(2):104–121. doi: 10.1097/JNC.0000000000000449

Table 3.

QOL Treatment Outcomes by Group at Follow-up

Outcomes by group and between-group contrasts POST Year 1 YEAR 2 Test of Trajectory Differences

Mean (SE) p d (95% CI) Mean (SE) p d (95% CI) Mean (SE) P d (95% CI) Time by Group Interaction

CES-Depression F(6, 485.49) = 0.36, p = 0.906
 Control 19.19 (1.04) - - 19.03 (1.11) - - 17.57 (1.32) - -
 10 Hrs. 19.26 (1.03) - - 19.18 (1.08) - - 18.99 (1.2) - -
 20 Hrs. 18.37 (0.96) - - 19.59 (1.05) - - 16.81 (1.19) - -
 Control vs. 10 Hrs. −0.07 (1.46) 0.961 −0.01 (−0.27, 0.25) −0.15 (1.55) 0.922 −0.01 (−0.29, 0.26) −1.43 (1.78) 0.424 −0.13 (−0.45, 0.19)
 Control vs. 20 Hrs. 0.82 (1.42) 0.564 0.07 (−0.18, 0.33) −0.56 (1.53) 0.715 −0.05 (−0.32, 0.22) 0.76 (1.78) 0.67 0.07 (−0.25, 0.38)
 10 Hrs. vs. 20 Hrs. 0.89 (1.41) 0.529 0.08 (−0.17, 0.33) −0.41 (1.51) 0.788 −0.04 (−0.30, 0.23) 2.18 (1.69) 0.197 0.20 (−0.10, 0.50)
Locus of Control F(6, 486.8) = 1.35, p = 0.234
 Control 28.47 (0.52) - - 28.67 (0.56) - - 29.9 0(0.67) - -
 10 Hrs. 28.31 (0.52) - - 27.91 (0.55) - - 27.57 (0.61) - -
 20 Hrs. 28.74 (0.49) - - 27.76 (0.53) - - 28.75 (0.60) - -
 Control vs. 10 Hrs. 0.17 (0.74) 0.819 0.03 (−0.21, 0.26) 0.76 (0.78) 0.333 0.12 (−0.13, 0.37) 2.33 (0.90) 0.01 0.38 (0.09, 0.67)
 Control vs. 20 Hrs. −0.26 (0.72) 0.712 −0.04 (−0.27, 0.19) 0.91 (0.78) 0.24 0.15 (−0.10, 0.40) 1.16 (0.90) 0.2 0.19 (−0.10, 0.48)
 10 Hrs. vs. 20 Hrs. −0.43 (0.71) 0.545 −0.07 (−0.3, 0.16) 0.15 (0.76) 0.842 0.02 (−0.22, 0.27) −1.18 (0.86) 0.169 −0.19 (−0.47, 0.08)
PSQI Sleep Quality F(6, 490.32) = 2.44, p = 0.024
 Control 9.1 (0.45) - - 9.54 (0.49) - - 8.14 (0.58) - -
 10 Hrs. 9.7 (0.45) - - 10.78 (0.47) - - 9.63 (0.53) - -
 20 Hrs. 9.04 (0.42) - - 8.83 (0.46) - - 9.65 (0.52) - -
 Control vs. 10 Hrs. −0.6 (0.64) 0.347 −0.14 (−0.43, 0.15) −1.24 (0.68) 0.068 −0.29 (−0.59, 0.02) −1.49 (0.78) 0.057 −0.34 (−0.70, 0.01)
 Control vs. 20 Hrs. 0.07 (0.62) 0.913 0.02 (−0.27, 0.3) 0.71 (0.67) 0.29 0.16 (−0.14, 0.47) −1.51 (0.78) 0.054 −0.35 (−0.70, 0.01)
 10 Hrs. vs. 20 Hrs. 0.67 (0.62) 0.28 0.15 (−0.13, 0.43) 1.96 (0.66) 0.003 0.45 (0.15, 0.75) −0.02 (0.74) 0.982 0 (−0.34, 0.33)
MOS-HIV General Health Perceptions F(6, 482.04) = 0.14, p = 0.992
 Control 52.5 (2.38) - - 52.49 (2.56) - - 53.96 (3.03) - -
 10 Hrs. 54.52 (2.38) - - 52.57 (2.49) - - 52.86 (2.77) - -
 20 Hrs. 53.55 (2.23) - - 52.6 (2.43) - - 55.18 (2.73) - -
 Control vs. 10 Hrs. −2.02 (3.36) 0.548 −0.08 (−0.32, 0.17) −0.08 (3.57) 0.982 0 (−0.26, 0.26) 1.11 (4.11) 0.788 0.04 (−0.26, 0.34)
 Control vs. 20 Hrs. −1.05 (3.27) 0.748 −0.04 (−0.28, 0.2) −0.12 (3.54) 0.974 0 (−0.26, 0.25) −1.22 (4.09) 0.765 −0.05 (−0.34, 0.25)
 10 Hrs. vs. 20 Hrs. 0.97 (3.27) 0.766 0.04 (−0.2, 0.27) −0.04 (3.49) 0.992 0 (−0.26, 0.25) −2.33 (3.89) 0.551 −0.09 (−0.37, 0.20)
MOS-HIV HRQoL - Physical Summary F(6, 482.14) = 0.79, p = 0.581
 Control 44.98 (0.95) - - 44.08 (1.01) - - 45.7 (1.20) - -
 10 Hrs. 44.77 (0.94) - - 46.74 (0.98) - - 46.5 (1.09) - -
 20 Hrs. 46.07 (0.88) - - 44.75 (0.96) - - 46.77 (1.08) - -
 Control vs. 10 Hrs. 0.22 (1.33) 0.872 0.02 (−0.21, 0.25) -2.66 (1.41) 0.06 −0.23 (−0.47, 0.01) −0.8 (1.62) 0.62 −0.07 (−0.35, 0.21)
 Control vs. 20 Hrs. −1.08 (1.30) 0.403 −0.09 (−0.31, 0.13) −0.67 (1.40) 0.63 −0.06 (−0.3, 0.18) −1.08 (1.62) 0.505 −0.09 (−0.37, 0.18)
 10 Hrs. vs. 20 Hrs. −1.30 (1.29) 0.315 −0.11 (−0.33, 0.11) 1.99 (1.38) 0.149 0.17 (−0.06, 0.41) −0.27 (1.54) 0.859 −0.02 (−0.29, 0.24)
MOS-HIV HRQoL - Mental Summary F(6, 479.08) = 0.61, p = 0.719
 Control 45.81 (1.05) - - 46.49 (1.12) - - 48.15 (1.33) - -
 10 Hrs. 48.12 (1.05) - - 48.39 (1.10) - - 48.6 (1.21) - -
 20 Hrs. 47.47 (0.98) - - 47.11 (1.06) - - 50.12 (1.20) - -
 Control vs. 10 Hrs. −2.31 (1.49) 0.121 −0.2 (−0.45, 0.05) −1.90 (1.57) 0.226 −0.16 (−0.43, 0.1) −0.45 (1.80) 0.803 −0.04 (−0.34, 0.26)
 Control vs. 20 Hrs. −1.66 (1.44) 0.249 −0.14 (−0.39, 0.10) −0.62 (1.55) 0.689 −0.05 (−0.31, 0.21) −1.97 (1.79) 0.271 −0.17 (−0.47, 0.13)
 10 Hrs. vs. 20 Hrs. 0.65 (1.44) 0.653 0.06 (−0.19, 0.30) 1.28 (1.53) 0.404 0.11 (−0.15, 0.37) −1.52 (1.71) 0.374 −0.13 (−0.42, 0.16)

Notes. Estimates from longitudinal models adjusted for baseline outcome, baseline MOS-HIV General Health Perception, baseline MOS-HIV Physical Summary, baseline number of prescriptions, and Nadir CD4. Cohen’s d: ~0.2 small, ~0.5 medium, ~0.8 large. CES-Depression = Center for Epidemiological Studies Depression Scale; HRQoL = health-related quality of life; MOS-HIV = Medical Outcomes Study – HIV; PSQI = Pittsburgh Sleep Quality Index; SE = Standard Error. No test of trajectory differences was statistically significant at a 10% False Discovery Rate level.