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. 2024 Jul 1;20(7):1209–1211. doi: 10.5664/jcsm.11120

Table 1.

Summary of treatments considered or trialed in our patient.

Treatment Dose Result
Baclofen 30 mg daily Effective, decreasing episodes from 15–20 to 1–6 nightly, but caused excess somnolence
Pelvic physiotherapy Consistently for 6 months Ineffective
Imipramine 80 mg daily Helped return to sleep, but still symptoms to some degree
Clonazepam 0.25 mg nightly Helped return to sleep, but still symptoms to some degree
Tadalafil 5 mg nightly Ineffective
Cinitapride Unable to attain in the United States
Oxycodone 5 mg daily Treated for 5 hours per night, but only took temporarily for postoperative pain
Morphine sulfate extended release 10 mg daily Effective for 1–2 weeks, then symptoms returned
Vitamin B Self-trialed, unclear dose Ineffective
Iron Self-trialed, unclear dose Ineffective
Selenium Self-trialed, unclear dose Ineffective
Sodium oxybate 2.75 g twice nightly up to 3 g three times nightly Effectively treated, allowing him to sleep 7.5 to 9 hours without symptoms