Table 1.
Summary of treatments considered or trialed in our patient.
| Treatment | Dose | Result |
|---|---|---|
| Baclofen | 30 mg daily | Effective, decreasing episodes from 15–20 to 1–6 nightly, but caused excess somnolence |
| Pelvic physiotherapy | Consistently for 6 months | Ineffective |
| Imipramine | 80 mg daily | Helped return to sleep, but still symptoms to some degree |
| Clonazepam | 0.25 mg nightly | Helped return to sleep, but still symptoms to some degree |
| Tadalafil | 5 mg nightly | Ineffective |
| Cinitapride | — | Unable to attain in the United States |
| Oxycodone | 5 mg daily | Treated for 5 hours per night, but only took temporarily for postoperative pain |
| Morphine sulfate extended release | 10 mg daily | Effective for 1–2 weeks, then symptoms returned |
| Vitamin B | Self-trialed, unclear dose | Ineffective |
| Iron | Self-trialed, unclear dose | Ineffective |
| Selenium | Self-trialed, unclear dose | Ineffective |
| Sodium oxybate | 2.75 g twice nightly up to 3 g three times nightly | Effectively treated, allowing him to sleep 7.5 to 9 hours without symptoms |