Table 1b:
Histological characteristics at diagnosis of AAV-GN of all patients and of whose who developed or not developed ESKD.
| Histological characteristics | All (n = 152) | ESKD (n = 59) | no ESKD (n = 93) | P-value |
|---|---|---|---|---|
| Total glomeruli n | 17 (12–25.3) | 17 (12–25.5) | 17 (12–25) | 0.48 |
| Percentage of normal glomeruli | 21.4 (7.4–40) | 9 (0–23.5) | 29 (14–50) | .000056 |
| Percentage of glomerular hyalinosis | 16.1 (7–33) | 19.4 (8–41.2) | 14 (5.7–29) | .031 |
| Percentage of glomeruli with extracapillary proliferation | 27.6 (14–58) | 29.6 (20.5–66.3) | 26 (12.5–50) | .82 |
| Percentage of glomeruli with sclerotic extracapillary proliferation, mean (SD) | 9.2 (13.9) | 10.4 (14.6) | 8.3 (13.5) | .35 |
| Specimen with endoarteritis, n (%) | 7 (4.6) | 4 (6.8) | 3 (3.2) | .31 |
| Specimen granulomatous interstitial nephritis, n (%) | 47 (30.9) | 20 (33.9) | 27 (29) | .54 |
| Specimen with interstitial nephritis, n (%) | 113 (74.3) | 48 (81.4) | 65 (69.9) | .1 |
| Specimen with tubulitis, n (%) | 31 (20.4) | 14 (23.7) | 17 (18.3) | .41 |
| Grade of interstitial fibrosis and tubular atrophy, n (%) | .039 | |||
| Absent | 33 (21.7) | 11 (18.6) | 22 (23.7) | |
| Mild | 55 (36.2) | 15 (25.4) | 40 (43) | |
| Moderate | 32 (21.1) | 18 (30.5) | 14 (15.1) | |
| Severe | 30 (19.7) | 14 (23.7) | 16 (17.2) |
If not otherwise specified, data are reported as median and IQR.