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. 2015 Jun 3;2015(6):CD010432. doi: 10.1002/14651858.CD010432.pub2

Comparison 3. IDA versus DOX.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 CR‐overall analysis 2 187 Risk Ratio (M‐H, Fixed, 95% CI) 1.28 [1.03, 1.59]
2 CR‐sensitivity analysis by random‐effects analysis 2 187 Risk Ratio (M‐H, Random, 95% CI) 1.29 [1.04, 1.60]
3 CR‐subgroup analysis by dose of IDA 2   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 12 mg/m²/d 1 87 Risk Ratio (M‐H, Fixed, 95% CI) 1.43 [1.06, 1.95]
3.2 20 mg/m²/d 1 100 Risk Ratio (M‐H, Fixed, 95% CI) 1.15 [0.85, 1.57]
4 CR‐subgroup by AML subtype 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 APL 1 12 Risk Ratio (M‐H, Fixed, 95% CI) 1.0 [0.50, 2.00]
4.2 non‐APL AML 1 88 Risk Ratio (M‐H, Fixed, 95% CI) 1.16 [0.83, 1.62]