TABLE 4.
Results of 5-flucytosine antifungal susceptibility test by disk diffusion and VITEK2 method
| Sample ID | Clade | Disk diffusion | VITEK2 | Gene mutation | ||
|---|---|---|---|---|---|---|
| Zones of inhibition diameter (mm) | Resistance profile | MIC (mg/L) | Resistance profile | FCY1 | ||
| 101019 | Clade I | 6 | R | ≥64 | R | S70R |
| 101008 | Clade I | 36 | S | ≤1 | S | S70R |
| 101009 | Clade I | 30 | S | ≤1 | S | S70R |
| 101022 | Clade I | 35 | S | ≤1 | S | S70R |
| 101077 | Clade I | 34 | S | ≤1 | S | S70R |
| 101082 | Clade I | 34 | S | ≤1 | S | S70R |
| 101101 | Clade I | 30 | S | ≤1 | S | S70R |
| 101087 | Clade I | 33 | S | ≤1 | S | S70R |
| 102096 | Clade VI | 32 | S | ≤1 | S | –b |
| 102170 | Clade VI | 31 | S | ≤1 | S | –b |
a
S = susceptible, I = intermediate, and R = resistant. The categorization of resistance was based on established clinical breakpoints provided by the Clinical and Laboratory Standards Institute.
b
–, absent.