Fig 6.

PLS-DA based on VOC abundance normalized matrix. (A) First and second components were used to plot samples onto a bidimensional graph. Green and blue colors indicate probiotic (n = 29) and placebo (n = 14) groups, respectively. (B) Cross-validated accuracy/R2/Q2 coefficients produced as a result of a permutation analysis between five predictive components. (C) PLS-DA VIP plot was computed based on the complete panel of detected VOC. Mostly important metabolite features identified by PLS-DA are ranked at the top. Blue and red boxes on the right indicate relative concentration of corresponding VOC for samples belonging to placebo and probiotic groups.