TABLE 3.

MBCs of rifamycins against virulent C. burnetii in A-498 host cells^a,b

	Rifampin	Rifabutin	Rifapentine	Rifaximin
Cmax (Reference)	7 (oral); 17.5 (IV) (27)	0.375 (29)	15.05 (41)	0.0096 (28)
NMI (ST16)	>0.1 – ≤17.5	0.1	>0.1 – ≤15.05	NBD
HPF-GA1 (ST16/26)	>0.1 – ≤17.5	0.1	0.1	NBD
CM-SC1 (ST20)	>0.1 – ≤17.5	0.1	0.1	NBD
GP-CO1 (ST8)	>0.1 – ≤17.5	0.1	0.1	NBD

^a All values are expressed as microgram per milliliter.

^b NBD, no bactericidal activity detected at the tested concentration(s).