Figure 9: OptoProfilin clustering response to different cellular stress inputs.
A. A light-activated clustering response is observed in response to numerous stress inputs in HeLa cells, including oxidative stress (0.5 mM Sodium Arsenite, 15 min pre-treatment), Osmotic stress (200 mM Sorbitol, 15 min pre-treatment), Senescence (2 h treatment with 200 μM H2O2, imaged 72 h post-treatment). Heat shock (46 °C, 1 h) did not induce a clustering response. B. Quantification of experiments described in panel A. Scale bars=10 microns.
