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. 2023 Dec 15;326(2):H418–H425. doi: 10.1152/ajpheart.00729.2023

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Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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Figure 3. — Lack of acute empagliflozin (EMPA) effects on peak Na⁺ current (I_Na) of mdx ventricular cardiomyocytes. A: peak I_Na before, during superfusion with bath solution containing 1 µM EMPA (light blue), and after washout over time (n = 13 cells from 2 mdx hearts). Data are expressed as means ± SE. Inset: pulse protocol, applied at 1-Hz frequency and elicited I_Na at the very beginning of the experiment. B: equivalent experiment as described in A at 10-Hz frequency (n = 15 cells from 2 mdx hearts).