Table 1.
Phenotypic features of female and castrated male Ossabaw minipigs and female, male, and castrated male Göttingen minipigs for mesenteric vasomotor assay
| Ossabaw Minipigs | Göttingen Minipigs | P Value | |
|---|---|---|---|
| Minipigs, n | |||
| Females | 19 | 9 | |
| Males | – | 22 | |
| Castrated males | 11 | 9 | |
| Age, mo | 18 ± 2 | 15 ± 2 | <0.05 |
| Body weight, kg | 55 ± 6 | 38 ± 8 | <0.05 |
| Temperature, °C | 37 ± 3 | 38 ± 1 | |
| Heart rate, beats/min | 99 ± 10 | 108 ± 12 | <0.05 |
| Left ventricular pressure, mmHg | 94 ± 11 | 84 ± 10 | <0.05 |
| Erythrocytes,106/mm3 | 5.9 ± 0.7 | 5.8 ± 0.8 | |
| Leukocytes,103/mm3 | 7.7 ± 1.4 | 5.9 ± 1.3 | <0.05 |
| Platelets, 103/mm3 | 262 ± 41 | 452 ± 88 | <0.05 |
| Na+, mmol/L | 144 ± 6 | 142 ± 3 | |
| K+, mmol/L | 3.7 ± 0.3 | 4.1 ± 0.5 | <0.05 |
| Glucose, mg/dL | 131 ± 56 | 100 ± 34 | <0.05 |
| Cholesterol, mg/dL | 74 ± 11 | 62 ± 20 | <0.05 |
| HDL, mg/dL | 31 ± 6 | 32 ± 9 | |
| LDL, mg/dL | 33 ± 7 | 22 ± 11 | <0.05 |
| Triglycerides, mg/dL | 41 ± 14 | 44 ± 13 | |
| hs-CRP, mg/dL | <0.02 | <0.02 | |
| AST, U/L | 48 ± 10 | 37 ± 7 | <0.05 |
| GPT, U/L | 81 ± 23 | 49 ± 9 | <0.05 |
| Creatinine, mg/dL | 1.03 ± 0.17 | 0.77 ± 0.18 | <0.05 |
Values are means ± SD. AST, aspartate aminotransferase; GPT, glutamate pyruvate transaminase; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoproteins. Unpaired Student’s t test.