TABLE 1.
Infectivity in HeLa cells expressing various numbers of CD4 and CCR5 molecules on their surfacea
| Cell line | CD4 level | CCR5 level | No. of foci/wellb
|
|||
|---|---|---|---|---|---|---|
| SF162 | GM186 | GM154 (Nt) | GM195 (Ct) | |||
| HI-R | Low | Absent | 5 | 7 | 5 | 5 |
| HI-J | High | Absent | 8 | 9 | 5 | 5 |
| RC-12 | Low | Intermediate | 50 | 50 | 10 | 10 |
| JC-10 | High | Low | 650 | 600 | 50 | 75 |
| JC-53 | High | High | 700 | 750 | 150 | 350 |
a
CD4 and CCR5 expression levels were reported previously (42). The values in this table represent the number of foci per well (average of three wells). One representative out of three independent experiments is shown.
b
Nt and Ct, amino- and carboxy-terminal, respectively, sides of the V2 loop.