Table 5.

Multiple Logistic Regression of Interleukin-6 Tertiles across Select Outcomes

IL-6 Levels	No Renal Impairment	p-value	AKI	p-value	CKD	p-value
Mortality
Low (<51 pg/mL)	1.00		1.00		1.00
Intermediate (51 to 251 pg/mL)	2.81 (1.44-5.50)	0.01*	4.22 (2.14-8.31)	<0.01*	4.86 (1.46-16.15)	0.01*
High (>251 pg/mL)	8.03 (4.24-15.21)	<0.01*	7.93 (4.12-15.27)	<0.01*	10.14 (3.15-32.60)	<0.01*
Intubation
Low (<51 pg/mL)	1.00		1.00		1.00
Intermediate (51 to 251 pg/mL)	2.20 (1.23-3.92)	0.01*	4.07 (2.15-7.72)	<0.01*	3.06 (1.07-8.72)	0.04*
High (>251 pg/mL)	6.14 (3.51-10.72)	<0.01*	6.67 (3.59-12.38)	<0.01*	7.08 (2.56-19.63)	<0.01*
Discharge
Low (<51 pg/mL)	1.00		1.00		1.00
Intermediate (51 to 251 pg/mL)	0.38 (0.20-0.74)	0.01*	0.24 (0.12-0.48)	<0.01*	0.21 (0.06-0.68)	0.01*
High (>251 pg/mL)	0.13 (0.07-0.25)	<0.01*	0.13 (0.07-0.24)	<0.01*	0.10 (0.03-0.32)	<0.01*
LOS >14
Low (<51 pg/mL)	1.00		1.00		1.00
Intermediate (51 to 251 pg/mL)	1.58 (1.06-2.35)	0.03*	0.49 (0.27-0.87)	0.02*	1.06 (0.45-2.51)	0.89
High (>251 pg/mL)	2.63 (1.72-4.02)	<0.01*	0.44 (0.25-0.76)	0.01*	0.59 (0.26-1.35)	0.21