Table 1.

Demographic information of participants in this study

	Discovery set	Replication set
N	26,789	3039
Age (years; mean ± sd)	55.22 (7.43)	52.92(7.34)
Sex (female; percent)	14,041 (52.4)	1621 (53.3)
BMI	26.57 (4.17)	26.34 (4.14)
Educational qualification (%)
A levels	1520 (5.7)	172 (5.7)
College	12,061 (45.2)	1404 (46.3)
CSE	726 (2.7)	88 (2.9)
None of above	1830 (6.9)	138 (4.6)
NVQ	4142 (15.5)	529 (17.5)
O levels	2966 (11.1)	332 (11.0)
Other	3451 (12.9)	368 (12.1)
Smoking status (%)
Never	16,335 (61.1)	1938 (63.9)
Previous	8863 (33.1)	932 (30.7)
Current	1543 (5.8)	164 (5.4)
Drinking status (%)
Never	519 (1.9)	58 (1.9)
Previous	552 (2.1)	46 (1.5)
Current	25,712 (96.0)	2935 (96.6)