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ΔICP35 mutant capsids contain aberrant internal cores. Electron micrographs of thin sections of sucrose gradient-purified B capsids obtained from (A) HSV-1 KOS-infected cells and (B) ΔICP35 mutant virus-infected cells. Arrows indicate representative capsids. Bars, 100 nm. Negatives were scanned and prepared for presentation using Adobe PhotoShop 5.0.
